{"id":5038,"date":"2021-01-04T22:05:09","date_gmt":"2021-01-04T14:05:09","guid":{"rendered":"http:\/\/simedarbyoilsnutrition.com\/?post_type=news&p=5038"},"modified":"2021-01-04T22:05:11","modified_gmt":"2021-01-04T14:05:11","slug":"tackling-stroke-with-palm-vitamin-e-tocotrienols","status":"publish","type":"news","link":"https:\/\/sdguthrie-nutrition.com\/en\/news\/tackling-stroke-with-palm-vitamin-e-tocotrienols\/","title":{"rendered":"Tackling stroke with palm Vitamin E tocotrienols"},"content":{"rendered":"

Published on June 2, 20<\/em>13 on The Star<\/p>

Written by: Fiona Ho<\/p>

Recent studies conducted by the Ohio State University have found that a natural compound of vitamin E called alpha-tocotrienols may play a role in reducing stroke-related damage.<\/strong><\/p>

IMAGINE having the world you know ripped from beneath your feet. Your vision blurs. Colours once resoundingly familiar grow faint.<\/p>

Your memory fails you. Abilities you have been well-acquainted with from infancy, including the simple acts of walking and talking, become a daily struggle.<\/p>

Having a stroke can leave you with severe and lasting debilitations.<\/p>

Currently, it is also the leading cause of serious long-term disability around the world.<\/p>

Strokes occur when the blood flow to your brain is halted. Within minutes, brain cells become damaged and may die.<\/p>

When this occurs, the body parts that are controlled by these cells can no longer function.<\/p>

This loss of function may range from mild to severe, or temporary or permanent; depending on where and how much of the brain is damaged, as well as how fast the blood supply can be returned to the affected areas.<\/p>

Types of stroke<\/strong><\/p>

There are two types of stroke. The more common one, called ischaemic stroke, is caused by blood clots that block the blood vessels to the brain.<\/p>

About 87% of all strokes are ischaemic in nature.<\/p>

The other kind, called haemorrhagic stroke, occurs when there is bleeding in the brain.<\/p>

Meanwhile, \u201cmini-strokes\u201d or transient ischemic attacks (TIAs) occur when the blood supply to the brain is briefly interrupted.<\/p>

According to the World Health Organization (WHO), stroke results in the fourth highest burden of disease worldwide.<\/p>

In Malaysia, stroke is actually the third biggest cause of death.<\/p>

Of the individuals surviving stroke, around 70% will experience severe disability immediately after, and 30% will still be experiencing severe disability after 12 months.<\/p>

A stroke can happen to anyone, but the risk of getting one increases with age.<\/p>

After the age of 55, the risk of suffering from a stroke doubles for every decade a person is alive.<\/p>

At 45 years of age, the chance of having a stroke in the next 20 years is approximately one in 30.<\/p>

However, an increasing number of strokes have been reported in people under the age of 40.<\/p>

Health experts attribute this trend to lifestyle factors such as physical inactivity, heavy drinking and smoking.<\/p>

Such lifestyle choices may contribute to risk factors such as hypertension, diabetes, atrial fibrillation (which produces an irregular heartbeat), and high cholesterol.<\/p>

Acute stroke therapies try to stop a stroke while it is happening by quickly dissolving the blood clot or by stopping the bleeding.<\/p>

Post-stroke rehabilitation helps individuals overcome disabilities that result from stroke damage.<\/p>

Drug therapy with blood thinners is the most common treatment for stroke.<\/p>

Tocotrienols in stroke prevention<\/strong><\/p>

Recent studies conducted by the Ohio State University scientists have found that a natural compound of vitamin E called alpha-tocotrienol may have neuroprotective properties that can play a role in reducing stroke-induced damage.<\/p>

Vitamin E occurs naturally in eight different forms: four tocopherols and four tocotrienols \u2013 each named alpha, beta, delta and gamma. The more commonly known form of vitamin E is tocopherols. However, with continuing research, tocotrienols are fast emerging as the superior siblings in the vitamin E family that is also necessary to provide a full range of antioxidant properties in vitamin E.<\/p>

The vitamin E derivative is a common component of a typical Southeast Asian diet that is found in rice bran, coconut oil, cocoa butter, barley, wheat germ and palm oil. However, tocotrienols are most abundantly found in palm oil.<\/p>

About 75% of vitamin E from palm oil comprises of tocotrienols.<\/p>

Prof Chandan K. Sen, professor and vice chair for research in Ohio State\u2019s department of surgery and senior author of a study on stroke prevention informed that that their research has shown that alpha-tocotrienol can trigger production of a protein in the brain that clears toxins from nerve cells.<\/p>

This helps to prevent those cells from dying after a stroke.<\/p>

\u201cThe main emphasis of our study is what you call \u2018secondary prevention\u2019. In many cases, stroke is preceded by TIAs or a mini-stroke.<\/p>

\u201cWe know that one in five people who have had a mini-stroke will get a full-blown stroke within a year. This is where we intervene, to make sure that the full-blown stroke doesn\u2019t come about,\u201d he says.<\/p>

This neuroprotective property is among the three mechanisms that tocotrienols exhibit to protect brain cells after a stroke, according to the Ohio State University scientists who have studied the nutrient for more than a decade.<\/p>

In the case of stroke, blood clots are dangerous because they can block arteries and cut off blood flow, a process leading to ischaemia (lack of blood).<\/p>

Prof Chandan, who has led numerous studies on how vitamin E tocotrienols can protect the brain against stroke damage in animal and cell models, says that their research has found that alpha-tocotrienols also act as an antithrombotic agent, which can help prevent or interfere with the formation of a thrombus or blood clotting.<\/p>

The team also found evidence that tocotrienol has arteriogenic properties that could help protect the brain against the damage caused by stroke, says Prof Chandan.<\/p>

Arteriogenesis refers to an increase in the diameter of existing arterial (blood) vessels.<\/p>

\u201cIn recovering from a stroke, we have found that alpha-tocotrienols have the ability to irrigate the injured part of the brain through arteriogenesis, a process that assists in vascularisation of the brain.\u201d<\/p>

The induced growth of collateral arteries may reduce ischaemic injury in endangered territories.<\/p>

The good news is that about 80% of all strokes are preventable. It begins with managing the key risk factors. Because the risk factors of stroke are well-defined, an effective scoring mechanism can help to evaluate your overall risk of getting a stroke.<\/p>

\u201cObviously, if you are in the risky category, you should look into preventive measures, rather than wait until a stroke happens and then go for treatment,\u201d Prof Chandan points out.<\/p>

The researcher adds: \u201cThe best thing about tocotrienol is, because it is not a drug, it has no toxicity and the risk of addiction is absent.<\/p>

\u201cThere is also evidence that tocotrienols can be beneficial in cholesterol management, one of the key risk factors for stroke. It is a natural remedy that can easily be applied as a form of effective stroke preventive measure,\u201d he concludes.<\/p>

Reference:<\/p>

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